During the yearly visits, a pelvic exam is carried out with assortment of the identical specimens as in the first go to, aside from citrated blood for plasma and entire blood for CBC. Women with LSIL or with ASC-US HPV positive are adopted every 6 months till they’ve three consecutive normal cytologies (see below). During the 6-month visit, no pelvic examination was carried out unless the girl had an ASC-US constructive for HPV DNA or LSIL interpretation of the enrollment cytology. The nurse transferred the swab to a 10-ml vial with three ml of PreservCyt resolution and positioned it immediately in liquid nitrogen. Women who required a pelvic exam had each the clinician-collected specimen and the self-collected one (see results section).
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- HC2™ testing was performed on enrollment (pre-vaccination) specimens utilizing a 2ml aliquot of exfoliated cells saved in Preservcyt.
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In desk 5, we present chosen traits detected in the bodily exam and cytology. About 65% of women had regular or decrease than normal weight in accordance with WHO classification utilizing the body mass index, 22% had been overweight and 13% obese. Reproductive, contraceptive and smoking habits of examine individuals. Detailed standard procedures had been developed for the proper labeling, transportation, processing and cargo of specimens, with specific emphasis on maintenance and monitoring of the cold chain.
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The house visits after the first dose had been accomplished for 98% of individuals and people after the second and third were accomplished for 97% of individuals. Exfoliated cells for cytology, HPV DNA, CT DNA, GC DNA and different testing were collected with a Cervex brush by firmly rotating the brush 5 occasions 360° around the cervical os. In ladies whose cervix exhibited extensive ectopy, the cervex brushing was also used on the ectocervix to insure sampling of the squamo-columnar junction. The brush was vigorously rinsed in liquid transport medium (PreservCyt) and saved in coolers at about 20° Celsius.
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